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好难 · 发表于 2014-6-6 01:20:35

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How Propecia works
Finasteride drops in both scalp and blood levels of DHT that causing hair loss. Finasteride 1-mg/day decreases serum DHT levels by almost 70%. Serum testosterone levels actually increased by 9%, but this is within the range of normal.
Using Propecia
During the first six months you may note some thinning of your existing hair. This may be due to either progression of your hair loss before finasteride has had a chance to work or some shedding of miniaturized hair that makes way for the new healthy anagen hair to grow. You should continue the medication for at least one year before you can assess its benefits.
Side Effects
Side effects from finasteride at the 1-mg dose are uncommon, but reversible. The five- year drug related side effects studied data showed that 4% of men taking finasteride 1mg experienced decreased libido, erectile dysfunction, and decreased volume of ejaculate.
Adverse Reactions
Adverse reactions related to the breast, including breast tenderness or breast enlargement (gynecomastia), occurred in 0.4% of men taking finasteride 1-mg (Propecia). Other reactions including rash, pruritus, urticarial (hives), swelling of the lips and face, and testicular pain.
Effects on PSA
Finasteride causes a decrease in serum PSA (prostate specific antigen) by approximately 50% in normal men. Since PSA levels are used to screen for prostate enlargement and prostate cancer, it is important that your personal physician is aware that you are taking Propecia (finasteride) so that he/she may take this into account when interpreting your PSA results.
Caution during Pregnancy
Women should not handle crushed or broken Propecia tablets when they are pregnant, or may potentially be pregnant. Exposure of pregnant women to semen from men treated with Propecia poses no risk to the fetus.
Long-Term Benefits and Risks
Results generally peak around one year and then are stable in the second year or decrease very slightly. Although the long-term ability of finasteride to maintain one’s hair is unknown, the majority of men find that after 5 years the medication is still working.
Increasing the Dose
There are published data demonstrating that 5 mg is no better than 1 mg from controlled clinical trials. In practice, often increase the dose when someone has been on the same dose of medication for about three years and then stops responding (begins to lose hair after being stable). When increasing the dose generally use generic finasteride 5mg, 1/3 pill a day.